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Microfocus computed tomography for fetal postmortem imaging: an overview
Over the last few years, fetal postmortem microfocus computed tomography (micro-CT) imaging has increased in popularity for both diagnostic and research purposes. Micro-CT imaging could be a substitute for autopsy, particularly in very early gestation fetuses for whom autopsy can be technically chal...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027643/ https://www.ncbi.nlm.nih.gov/pubmed/36169668 http://dx.doi.org/10.1007/s00247-022-05517-1 |
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author | Docter, Daniël Dawood, Yousif Jacobs, Karl Hagoort, Jaco Oostra, Roelof-Jan van den Hoff, Maurice J. B. Arthurs, Owen J. de Bakker, Bernadette S. |
author_facet | Docter, Daniël Dawood, Yousif Jacobs, Karl Hagoort, Jaco Oostra, Roelof-Jan van den Hoff, Maurice J. B. Arthurs, Owen J. de Bakker, Bernadette S. |
author_sort | Docter, Daniël |
collection | PubMed |
description | Over the last few years, fetal postmortem microfocus computed tomography (micro-CT) imaging has increased in popularity for both diagnostic and research purposes. Micro-CT imaging could be a substitute for autopsy, particularly in very early gestation fetuses for whom autopsy can be technically challenging and is often unaccepted by parents. This article provides an overview of the latest research in fetal postmortem micro-CT imaging with a focus on diagnostic accuracy, endovascular staining approaches, placental studies and the reversibility of staining. It also discusses new methods that could prove helpful for micro-CT of larger fetuses. While more research is needed, contrast-enhanced micro-CT has the potential to become a suitable alternative to fetal autopsy. Further research using this novel imaging tool could yield wider applications, such as its practise in imaging rare museum specimens. |
format | Online Article Text |
id | pubmed-10027643 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-100276432023-03-22 Microfocus computed tomography for fetal postmortem imaging: an overview Docter, Daniël Dawood, Yousif Jacobs, Karl Hagoort, Jaco Oostra, Roelof-Jan van den Hoff, Maurice J. B. Arthurs, Owen J. de Bakker, Bernadette S. Pediatr Radiol Espr Over the last few years, fetal postmortem microfocus computed tomography (micro-CT) imaging has increased in popularity for both diagnostic and research purposes. Micro-CT imaging could be a substitute for autopsy, particularly in very early gestation fetuses for whom autopsy can be technically challenging and is often unaccepted by parents. This article provides an overview of the latest research in fetal postmortem micro-CT imaging with a focus on diagnostic accuracy, endovascular staining approaches, placental studies and the reversibility of staining. It also discusses new methods that could prove helpful for micro-CT of larger fetuses. While more research is needed, contrast-enhanced micro-CT has the potential to become a suitable alternative to fetal autopsy. Further research using this novel imaging tool could yield wider applications, such as its practise in imaging rare museum specimens. Springer Berlin Heidelberg 2022-09-28 2023 /pmc/articles/PMC10027643/ /pubmed/36169668 http://dx.doi.org/10.1007/s00247-022-05517-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Espr Docter, Daniël Dawood, Yousif Jacobs, Karl Hagoort, Jaco Oostra, Roelof-Jan van den Hoff, Maurice J. B. Arthurs, Owen J. de Bakker, Bernadette S. Microfocus computed tomography for fetal postmortem imaging: an overview |
title | Microfocus computed tomography for fetal postmortem imaging: an overview |
title_full | Microfocus computed tomography for fetal postmortem imaging: an overview |
title_fullStr | Microfocus computed tomography for fetal postmortem imaging: an overview |
title_full_unstemmed | Microfocus computed tomography for fetal postmortem imaging: an overview |
title_short | Microfocus computed tomography for fetal postmortem imaging: an overview |
title_sort | microfocus computed tomography for fetal postmortem imaging: an overview |
topic | Espr |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027643/ https://www.ncbi.nlm.nih.gov/pubmed/36169668 http://dx.doi.org/10.1007/s00247-022-05517-1 |
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