Cargando…

A novel, extreme low-cost poly (Erythrosine) modified pencil graphite electrode for determination of Adrenaline

A simple, novel, and less cost yellow (Erythrosine) modified pencil graphite electrode (Po-ERY/MGPE) was successfully fabricated via electropolymerization method using cyclic voltammetric techniques. The fabricated Po-ERY/MGPE opted as a sensor for the detection of Adrenaline (ADR) in 0.2 M PBS (7.4...

Descripción completa

Detalles Bibliográficos
Autores principales: Sukanya, S. D., Swamy, B. E. Kumara, Shashikumara, J. K., Sharma, S. C., Hariprasad, S. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027675/
https://www.ncbi.nlm.nih.gov/pubmed/36941302
http://dx.doi.org/10.1038/s41598-023-31068-y
_version_ 1784909755546861568
author Sukanya, S. D.
Swamy, B. E. Kumara
Shashikumara, J. K.
Sharma, S. C.
Hariprasad, S. A.
author_facet Sukanya, S. D.
Swamy, B. E. Kumara
Shashikumara, J. K.
Sharma, S. C.
Hariprasad, S. A.
author_sort Sukanya, S. D.
collection PubMed
description A simple, novel, and less cost yellow (Erythrosine) modified pencil graphite electrode (Po-ERY/MGPE) was successfully fabricated via electropolymerization method using cyclic voltammetric techniques. The fabricated Po-ERY/MGPE opted as a sensor for the detection of Adrenaline (ADR) in 0.2 M PBS (7.4 pH). This reported senor displayed excellent electrocatalytic activity, increased sensitivity, high stability, superior electron transfer kinetics in the oxidation of ADR once relative to BGPE. The significance of pH, scan rate, and impact of concentration was assessed at the sensor. As per the pH and scan rate study, redox routes carry the same number of electrons and protons, and electro-oxidation of ADR was adsorption controlled respectively. The LOD of ADR was found to be 0.499 µM. The DPV data indicate that there is a significant peak divergence among ADR and uric acid (UA) which could make it easier to determine them alone and simultaneously on the sensor. The described method has been employed for the determination of ADR in injection sample. Good recovery values indicate the efficacy and applicability of the sensor in detecting ADR.
format Online
Article
Text
id pubmed-10027675
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-100276752023-03-22 A novel, extreme low-cost poly (Erythrosine) modified pencil graphite electrode for determination of Adrenaline Sukanya, S. D. Swamy, B. E. Kumara Shashikumara, J. K. Sharma, S. C. Hariprasad, S. A. Sci Rep Article A simple, novel, and less cost yellow (Erythrosine) modified pencil graphite electrode (Po-ERY/MGPE) was successfully fabricated via electropolymerization method using cyclic voltammetric techniques. The fabricated Po-ERY/MGPE opted as a sensor for the detection of Adrenaline (ADR) in 0.2 M PBS (7.4 pH). This reported senor displayed excellent electrocatalytic activity, increased sensitivity, high stability, superior electron transfer kinetics in the oxidation of ADR once relative to BGPE. The significance of pH, scan rate, and impact of concentration was assessed at the sensor. As per the pH and scan rate study, redox routes carry the same number of electrons and protons, and electro-oxidation of ADR was adsorption controlled respectively. The LOD of ADR was found to be 0.499 µM. The DPV data indicate that there is a significant peak divergence among ADR and uric acid (UA) which could make it easier to determine them alone and simultaneously on the sensor. The described method has been employed for the determination of ADR in injection sample. Good recovery values indicate the efficacy and applicability of the sensor in detecting ADR. Nature Publishing Group UK 2023-03-20 /pmc/articles/PMC10027675/ /pubmed/36941302 http://dx.doi.org/10.1038/s41598-023-31068-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Sukanya, S. D.
Swamy, B. E. Kumara
Shashikumara, J. K.
Sharma, S. C.
Hariprasad, S. A.
A novel, extreme low-cost poly (Erythrosine) modified pencil graphite electrode for determination of Adrenaline
title A novel, extreme low-cost poly (Erythrosine) modified pencil graphite electrode for determination of Adrenaline
title_full A novel, extreme low-cost poly (Erythrosine) modified pencil graphite electrode for determination of Adrenaline
title_fullStr A novel, extreme low-cost poly (Erythrosine) modified pencil graphite electrode for determination of Adrenaline
title_full_unstemmed A novel, extreme low-cost poly (Erythrosine) modified pencil graphite electrode for determination of Adrenaline
title_short A novel, extreme low-cost poly (Erythrosine) modified pencil graphite electrode for determination of Adrenaline
title_sort novel, extreme low-cost poly (erythrosine) modified pencil graphite electrode for determination of adrenaline
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027675/
https://www.ncbi.nlm.nih.gov/pubmed/36941302
http://dx.doi.org/10.1038/s41598-023-31068-y
work_keys_str_mv AT sukanyasd anovelextremelowcostpolyerythrosinemodifiedpencilgraphiteelectrodefordeterminationofadrenaline
AT swamybekumara anovelextremelowcostpolyerythrosinemodifiedpencilgraphiteelectrodefordeterminationofadrenaline
AT shashikumarajk anovelextremelowcostpolyerythrosinemodifiedpencilgraphiteelectrodefordeterminationofadrenaline
AT sharmasc anovelextremelowcostpolyerythrosinemodifiedpencilgraphiteelectrodefordeterminationofadrenaline
AT hariprasadsa anovelextremelowcostpolyerythrosinemodifiedpencilgraphiteelectrodefordeterminationofadrenaline
AT sukanyasd novelextremelowcostpolyerythrosinemodifiedpencilgraphiteelectrodefordeterminationofadrenaline
AT swamybekumara novelextremelowcostpolyerythrosinemodifiedpencilgraphiteelectrodefordeterminationofadrenaline
AT shashikumarajk novelextremelowcostpolyerythrosinemodifiedpencilgraphiteelectrodefordeterminationofadrenaline
AT sharmasc novelextremelowcostpolyerythrosinemodifiedpencilgraphiteelectrodefordeterminationofadrenaline
AT hariprasadsa novelextremelowcostpolyerythrosinemodifiedpencilgraphiteelectrodefordeterminationofadrenaline