Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms

Prolactin (PRL) is elevated in B-cell-mediated lymphoproliferative diseases and promotes B-cell survival. Whether PRL or PRL receptors drive the evolution of B-cell malignancies is unknown. We measure changes in B cells after knocking down the pro-proliferative, anti-apoptotic long isoform of the PR...

Descripción completa

Detalles Bibliográficos
Autores principales: Taghi Khani, Adeleh, Kumar, Anil, Sanchez Ortiz, Ashly, Radecki, Kelly C., Aramburo, Soraya, Lee, Sung June, Hu, Zunsong, Damirchi, Behzad, Lorenson, Mary Y., Wu, Xiwei, Gu, Zhaohui, Stohl, William, Sanz, Ignacio, Meffre, Eric, Müschen, Markus, Forman, Stephen J., Koff, Jean L., Walker, Ameae M., Swaminathan, Srividya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027679/
https://www.ncbi.nlm.nih.gov/pubmed/36941341
http://dx.doi.org/10.1038/s42003-023-04667-8

Ejemplares similares

Ejemplares similares