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Blimp-1/PRDM1 and Hr3/RORβ specify the blue-sensitive photoreceptor subtype in Drosophila by repressing the hippo pathway

During terminal differentiation of the mammalian retina, transcription factors control binary cell fate decisions that generate functionally distinct subtypes of photoreceptor neurons. For instance, Otx2 and RORβ activate the expression of the transcriptional repressor Blimp-1/PRDM1 that represses b...

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Detalles Bibliográficos
Autores principales: Bunker, Joseph, Bashir, Mhamed, Bailey, Sydney, Boodram, Pamela, Perry, Alexis, Delaney, Rory, Tsachaki, Maria, Sprecher, Simon G., Nelson, Erik, Call, Gerald B., Rister, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027706/
https://www.ncbi.nlm.nih.gov/pubmed/36960411
http://dx.doi.org/10.3389/fcell.2023.1058961