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Sialoadhesin (CD169/Siglec-1) is an extended molecule that escapes inhibitory cis-interactions and synergizes with other macrophage receptors to promote phagocytosis

Sialoadhesin (CD169/Siglec-1, Sn) is a macrophage receptor that interacts with sialic acids on both host cells and pathogens. It is a type 1 membrane protein with an unusually large number of 17 extracellular immunoglobulin (Ig)-like domains, made up of an N-terminal V-set domain that binds sialic a...

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Detalles Bibliográficos
Autores principales:	Klaas, Mariliis, Dubock, Stuart, Ferguson, David J. P., Crocker, Paul R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027830/ https://www.ncbi.nlm.nih.gov/pubmed/36738392 http://dx.doi.org/10.1007/s10719-022-10097-1

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