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Single-cell transcriptomics uncovers a non-autonomous Tbx1-dependent genetic program controlling cardiac neural crest cell development

Disruption of cardiac neural crest cells (CNCCs) results in congenital heart disease, yet we do not understand the cell fate dynamics as these cells differentiate to vascular smooth muscle cells. Here we performed single-cell RNA-sequencing of NCCs from the pharyngeal apparatus with the heart in con...

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Detalles Bibliográficos
Autores principales:	De Bono, Christopher, Liu, Yang, Ferrena, Alexander, Valentine, Aneesa, Zheng, Deyou, Morrow, Bernice E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027855/ https://www.ncbi.nlm.nih.gov/pubmed/36941249 http://dx.doi.org/10.1038/s41467-023-37015-9

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