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Loss of CD28 expression associates with severe T-cell exhaustion in acute myeloid leukemia

INTRODUCTION: Despite accumulated evidence in T-cell exhaustion in acute myeloid leukemia (AML), the immunotherapeutic targeting exhausted T cells such as programmed cell death protein 1 (PD-1) blockade in AML failed to achieve satisfying efficacy. Characteristics of exhausted T cells in AML remaine...

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Detalles Bibliográficos
Autores principales:	Huang, Yueting, Zheng, Huijian, Zhu, Yuwen, Hong, Yan, Zha, Jie, Lin, Zhijuan, Li, Zhifeng, Wang, Caiyan, Fang, Zhihong, Yu, Xingxing, Liu, Long, Xu, Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027902/ https://www.ncbi.nlm.nih.gov/pubmed/36960073 http://dx.doi.org/10.3389/fimmu.2023.1139517

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