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Losing a child to adolescent cancer: A register‐based cohort study of psychotropic medication use in bereaved parents

PURPOSE: To investigate the short‐ and long‐term risk of psychotropic medication use in parents who lose a child to cancer diagnosed in adolescence. METHODS: This is a Swedish nationwide register‐based study including 184 bereaved mothers and 184 bereaved fathers of 184 children diagnosed with cance...

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Autores principales: Hovén, Emma, Ljungman, Lisa, Sveen, Josefin, Skoglund, Charlotte, Ljungman, Gustaf, Ljung, Rickard, Wikman, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028064/
https://www.ncbi.nlm.nih.gov/pubmed/36218005
http://dx.doi.org/10.1002/cam4.5347
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author Hovén, Emma
Ljungman, Lisa
Sveen, Josefin
Skoglund, Charlotte
Ljungman, Gustaf
Ljung, Rickard
Wikman, Anna
author_facet Hovén, Emma
Ljungman, Lisa
Sveen, Josefin
Skoglund, Charlotte
Ljungman, Gustaf
Ljung, Rickard
Wikman, Anna
author_sort Hovén, Emma
collection PubMed
description PURPOSE: To investigate the short‐ and long‐term risk of psychotropic medication use in parents who lose a child to cancer diagnosed in adolescence. METHODS: This is a Swedish nationwide register‐based study including 184 bereaved mothers and 184 bereaved fathers of 184 children diagnosed with cancer in adolescence. Logistic regression analyses, adjusted for sociodemographic characteristics and history of mental health problems, were performed to estimate risk of a prescription of psychotropic medication (anxiolytics, hypnotics/sedatives, antidepressants) in cancer‐bereaved parents from 1 year before to 5 years after the child's death, with a general population sample of non‐bereaved parents (n = 3291) as referents. RESULTS: At the year of the child's death, 28%–36% of mothers and 11%–20% of fathers had a prescription of anxiolytics, hypnotics/sedatives or antidepressants. The corresponding percentages for non‐bereaved mothers and fathers were 7%–12% and 4%–7%, respectively. Compared to non‐bereaved mothers, bereaved mothers showed higher odds of prescriptions from 1 year before up to four (anxiolytics) and 5 years (hypnotics/sedatives and antidepressants) after the child's death. Bereaved fathers showed higher odds than non‐bereaved fathers of prescriptions from 1 year before up to the year of (anxiolytics and hypnotics/sedatives) and 1 year after (antidepressants) the child's death. No differences in odds between bereaved and non‐bereaved fathers were found at 2 years after the child's death. Being unmarried, born outside Sweden, and having a history of mental health problems were associated with higher odds of prescribed medications. CONCLUSIONS: Indicative of mental health problems of clinical importance, cancer‐bereaved parents had a higher prevalence of use of psychotropic medication. A decrease in medication use was evident with time, but still at 5 years after the child's death mothers displayed a higher use while fathers showed no difference to non‐bereaved fathers after 2 years.
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spelling pubmed-100280642023-03-22 Losing a child to adolescent cancer: A register‐based cohort study of psychotropic medication use in bereaved parents Hovén, Emma Ljungman, Lisa Sveen, Josefin Skoglund, Charlotte Ljungman, Gustaf Ljung, Rickard Wikman, Anna Cancer Med RESEARCH ARTICLES PURPOSE: To investigate the short‐ and long‐term risk of psychotropic medication use in parents who lose a child to cancer diagnosed in adolescence. METHODS: This is a Swedish nationwide register‐based study including 184 bereaved mothers and 184 bereaved fathers of 184 children diagnosed with cancer in adolescence. Logistic regression analyses, adjusted for sociodemographic characteristics and history of mental health problems, were performed to estimate risk of a prescription of psychotropic medication (anxiolytics, hypnotics/sedatives, antidepressants) in cancer‐bereaved parents from 1 year before to 5 years after the child's death, with a general population sample of non‐bereaved parents (n = 3291) as referents. RESULTS: At the year of the child's death, 28%–36% of mothers and 11%–20% of fathers had a prescription of anxiolytics, hypnotics/sedatives or antidepressants. The corresponding percentages for non‐bereaved mothers and fathers were 7%–12% and 4%–7%, respectively. Compared to non‐bereaved mothers, bereaved mothers showed higher odds of prescriptions from 1 year before up to four (anxiolytics) and 5 years (hypnotics/sedatives and antidepressants) after the child's death. Bereaved fathers showed higher odds than non‐bereaved fathers of prescriptions from 1 year before up to the year of (anxiolytics and hypnotics/sedatives) and 1 year after (antidepressants) the child's death. No differences in odds between bereaved and non‐bereaved fathers were found at 2 years after the child's death. Being unmarried, born outside Sweden, and having a history of mental health problems were associated with higher odds of prescribed medications. CONCLUSIONS: Indicative of mental health problems of clinical importance, cancer‐bereaved parents had a higher prevalence of use of psychotropic medication. A decrease in medication use was evident with time, but still at 5 years after the child's death mothers displayed a higher use while fathers showed no difference to non‐bereaved fathers after 2 years. John Wiley and Sons Inc. 2022-10-11 /pmc/articles/PMC10028064/ /pubmed/36218005 http://dx.doi.org/10.1002/cam4.5347 Text en © 2022 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle RESEARCH ARTICLES
Hovén, Emma
Ljungman, Lisa
Sveen, Josefin
Skoglund, Charlotte
Ljungman, Gustaf
Ljung, Rickard
Wikman, Anna
Losing a child to adolescent cancer: A register‐based cohort study of psychotropic medication use in bereaved parents
title Losing a child to adolescent cancer: A register‐based cohort study of psychotropic medication use in bereaved parents
title_full Losing a child to adolescent cancer: A register‐based cohort study of psychotropic medication use in bereaved parents
title_fullStr Losing a child to adolescent cancer: A register‐based cohort study of psychotropic medication use in bereaved parents
title_full_unstemmed Losing a child to adolescent cancer: A register‐based cohort study of psychotropic medication use in bereaved parents
title_short Losing a child to adolescent cancer: A register‐based cohort study of psychotropic medication use in bereaved parents
title_sort losing a child to adolescent cancer: a register‐based cohort study of psychotropic medication use in bereaved parents
topic RESEARCH ARTICLES
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028064/
https://www.ncbi.nlm.nih.gov/pubmed/36218005
http://dx.doi.org/10.1002/cam4.5347
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