Type I interferon autoantibodies in hospitalized patients with Middle East respiratory syndrome and association with outcomes and treatment effect of interferon beta‐1b in MIRACLE clinical trial

BACKGROUND: Type I interferons (IFNs) are essential antiviral cytokines induced upon respiratory exposure to coronaviruses. Defects in type I IFN signaling can result in severe disease upon exposure to respiratory viral infection and are associated with worse clinical outcomes. Neutralizing autoanti...

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Detalles Bibliográficos
Autores principales: Alotaibi, Faizah, Alharbi, Naif Khalaf, Rosen, Lindsey B., Asiri, Ayed Y., Assiri, Abdullah M., Balkhy, Hanan H., Al Jeraisy, Majed, Mandourah, Yasser, AlJohani, Sameera, Al Harbi, Shmeylan, Jokhdar, Hani A. Aziz, Deeb, Ahmad M., Memish, Ziad A., Jose, Jesna, Ghazal, Sameeh, Al Faraj, Sarah, Al Mekhlafi, Ghaleb A., Sherbeeni, Nisreen Murad, Elzein, Fatehi Elnour, AlMutairi, Badriah M., Al‐Dawood, Abdulaziz, Abdullah, Mashan L., Barhoumi, Tlili, Alenazi, Mohammed W., Almasood, Abdulrahman, Holland, Steven M., Arabi, Yaseen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028524/
https://www.ncbi.nlm.nih.gov/pubmed/36960162
http://dx.doi.org/10.1111/irv.13116

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