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Structural and Biochemical Insights into Post-Translational Arginine-to-Ornithine Peptide Modifications by an Atypical Arginase
[Image: see text] Landornamide A is a ribosomally synthesized and post-translationally modified peptide (RiPP) natural product with antiviral activity. Its biosynthetic gene cluster encodes—among other maturases—the peptide arginase OspR, which converts arginine to ornithine units in an unusual post...
Autores principales: | Mordhorst, Silja, Badmann, Thomas, Bösch, Nina M., Morinaka, Brandon I., Rauch, Hartmut, Piel, Jörn, Groll, Michael, Vagstad, Anna L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028609/ https://www.ncbi.nlm.nih.gov/pubmed/36791048 http://dx.doi.org/10.1021/acschembio.2c00879 |
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