Tumor-associated macrophages respond to chemotherapy by detrimental transcriptional reprogramming and suppressing stabilin-1 mediated clearance of EGF

INTRODUCTION: Tumor resistance to chemotherapy and metastatic relapse account for more than 90% of cancer specific mortality. Tumor-associated macrophages (TAMs) can process chemotherapeutic agents and impair their action. Little is known about the direct effects of chemotherapy on TAMs. METHODS: Th...

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Detalles Bibliográficos
Autores principales: Larionova, Irina, Kiselev, Artem, Kazakova, Elena, Liu, Tengfei, Patysheva, Marina, Iamshchikov, Pavel, Liu, Quan, Mossel, Dieuwertje M., Riabov, Vladimir, Rakina, Militsa, Sergushichev, Alexey, Bezgodova, Natalia, Vtorushin, Sergei, Litviakov, Nikolai, Denisov, Evgeny, Koshkin, Philipp, Pyankov, Denis, Tsyganov, Matvei, Ibragimova, Marina, Cherdyntseva, Nadezhda, Kzhyshkowska, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028613/
https://www.ncbi.nlm.nih.gov/pubmed/36960065
http://dx.doi.org/10.3389/fimmu.2023.1000497

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