Manganese(I)-Catalyzed Asymmetric Hydrophosphination of α,β-Unsaturated Carbonyl Derivatives

[Image: see text] Here we report catalytic asymmetric hydrophosphination of α,β-unsaturated carbonyl derivatives using a chiral Mn(I) complex as a catalyst. Through H–P bond activation, various phosphine-containing chiral products can be accessed via hydrophosphination of various ketone-, ester-, an...

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Detalles Bibliográficos
Autores principales: Postolache, Roxana, Pérez, Juana M., Castiñeira Reis, Marta, Ge, Luo, Sinnema, Esther G., Harutyunyan, Syuzanna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028696/
https://www.ncbi.nlm.nih.gov/pubmed/36892214
http://dx.doi.org/10.1021/acs.orglett.2c04256
Descripción
Sumario:[Image: see text] Here we report catalytic asymmetric hydrophosphination of α,β-unsaturated carbonyl derivatives using a chiral Mn(I) complex as a catalyst. Through H–P bond activation, various phosphine-containing chiral products can be accessed via hydrophosphination of various ketone-, ester-, and carboxamide-based Michael acceptors.

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