P1 Bacteriophage-Enabled Delivery of CRISPR-Cas9 Antimicrobial Activity Against Shigella flexneri

[Image: see text] The discovery of clustered, regularly interspaced, short palindromic repeats (CRISPR) and the Cas9 RNA-guided nuclease provides unprecedented opportunities to selectively kill specific populations or species of bacteria. However, the use of CRISPR-Cas9 to clear bacterial infections...

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Detalles Bibliográficos
Autores principales: Huan, Yang W., Torraca, Vincenzo, Brown, Russell, Fa-arun, Jidapha, Miles, Sydney L., Oyarzún, Diego A., Mostowy, Serge, Wang, Baojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028697/
https://www.ncbi.nlm.nih.gov/pubmed/36802585
http://dx.doi.org/10.1021/acssynbio.2c00465

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