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RNA-activated protein cleavage with a CRISPR-associated endopeptidase

CRISPR-Cas systems provide adaptive immune responses in prokaryotes against foreign genetic elements through RNA-guided nuclease activity. Recently, additional genes with non-nuclease functions have been found in genetic association with CRISPR systems, suggesting there may be other RNA-guided non-n...

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Detalles Bibliográficos
Autores principales: Strecker, Jonathan, Demircioglu, F. Esra, Li, David, Faure, Guilhem, Wilkinson, Max E., Gootenberg, Jonathan S., Abudayyeh, Omar O., Nishimasu, Hiroshi, Macrae, Rhiannon K., Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028731/
https://www.ncbi.nlm.nih.gov/pubmed/36423276
http://dx.doi.org/10.1126/science.add7450