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RNA-activated protein cleavage with a CRISPR-associated endopeptidase
CRISPR-Cas systems provide adaptive immune responses in prokaryotes against foreign genetic elements through RNA-guided nuclease activity. Recently, additional genes with non-nuclease functions have been found in genetic association with CRISPR systems, suggesting there may be other RNA-guided non-n...
Autores principales: | Strecker, Jonathan, Demircioglu, F. Esra, Li, David, Faure, Guilhem, Wilkinson, Max E., Gootenberg, Jonathan S., Abudayyeh, Omar O., Nishimasu, Hiroshi, Macrae, Rhiannon K., Zhang, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028731/ https://www.ncbi.nlm.nih.gov/pubmed/36423276 http://dx.doi.org/10.1126/science.add7450 |
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