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Sequence characteristics and an accurate model of high-occupancy target loci in the human genome
Enhancers and promoters are considered to be bound by a small set of TFs in a sequence-specific manner. This assumption has come under increasing skepticism as the datasets of ChIP-seq assays have expanded. Particularly, high-occupancy target (HOT) loci attract hundreds of TFs with seemingly no dete...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028745/ https://www.ncbi.nlm.nih.gov/pubmed/36945558 http://dx.doi.org/10.1101/2023.02.05.527203 |