Targeted Phasing of 2–200 Kilobase DNA Fragments with a Short-Read Sequencer and a Single-Tube Linked-Read Library Method

In the human genome, heterozygous sites are genomic positions with different alleles inherited from each parent. On average, there is a heterozygous site every 1–2 kilobases (kb). Resolving whether two alleles in neighboring heterozygous positions are physically linked—that is, phased—is possible wi...

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Detalles Bibliográficos
Autores principales: Mikhaylova, Veronika, Rzepka, Madison, Kawamura, Tetsuya, Xia, Yu, Chang, Peter L., Zhou, Shiguo, Pham, Long, Modi, Naisarg, Yao, Likun, Perez-Agustin, Adrian, Pagans, Sara, Boles, T. Christian, Lei, Ming, Wang, Yong, Garcia-Bassets, Ivan, Chen, Zhoutao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028795/
https://www.ncbi.nlm.nih.gov/pubmed/36945366
http://dx.doi.org/10.1101/2023.03.05.531179

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