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Genome-wide screen identifies host loci that modulate M. tuberculosis fitness in immunodivergent mice

Genetic differences among mammalian hosts and Mycobacterium tuberculosis (Mtb) strains determine diverse tuberculosis (TB) patient outcomes. The advent of recombinant inbred mouse panels and next-generation transposon mutagenesis and sequencing approaches has enabled dissection of complex host-patho...

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Detalles Bibliográficos
Autores principales:	Meade, Rachel K., Long, Jarukit E., Jinich, Adrian, Rhee, Kyu Y., Ashbrook, David G., Williams, Robert W., Sassetti, Christopher M., Smith, Clare M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028809/ https://www.ncbi.nlm.nih.gov/pubmed/36945430 http://dx.doi.org/10.1101/2023.03.05.528534

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