Functional profiling of the Toxoplasma genome during acute mouse infection

Within a host, pathogens encounter a diverse and changing landscape of cell types, nutrients, and immune responses. Examining host-pathogen interactions in animal models can therefore reveal aspects of infection absent from cell culture. We use CRISPR-based screens to functionally profile the entire...

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Detalles Bibliográficos
Autores principales: Giuliano, Christopher J., Wei, Kenneth J., Harling, Faye M., Waldman, Benjamin S., Farringer, Madeline A., Boydston, Elizabeth A., Lan, Tammy C. T., Thomas, Raina W., Herneisen, Alice L., Sanderlin, Allen G., Coppens, Isabelle, Dvorin, Jeffrey D., Lourido, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028831/
https://www.ncbi.nlm.nih.gov/pubmed/36945434
http://dx.doi.org/10.1101/2023.03.05.531216

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