GoM DE: interpreting structure in sequence count data with differential expression analysis allowing for grades of membership

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Parts-based representations, such as non-negative matrix factorization and topic modeling, have been used to identify structure from single-cell sequencing data sets, in particular structure that is not as well captured by clustering or other dimensionality reduction methods. However, interpreting t...

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Detalles Bibliográficos
Autores principales: Carbonetto, Peter, Luo, Kaixuan, Sarkar, Abhishek, Hung, Anthony, Tayeb, Karl, Pott, Sebastian, Stephens, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028846/
https://www.ncbi.nlm.nih.gov/pubmed/36945441
http://dx.doi.org/10.1101/2023.03.03.531029
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