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signifinder enables the identification of tumor cell states and cancer expression signatures in bulk, single-cell and spatial transcriptomic data

Over the last decade, many studies and some clinical trials have proposed gene expression signatures as a valuable tool for understanding cancer mechanisms, defining subtypes, monitoring patient prognosis, and therapy efficacy. However, technical and biological concerns about reproducibility have be...

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Detalles Bibliográficos
Autores principales: Pirrotta, Stefania, Masatti, Laura, Corrà, Anna, Pedrini, Fabiola, Esposito, Giovanni, Martini, Paolo, Risso, Davide, Romualdi, Chiara, Calura, Enrica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028855/
https://www.ncbi.nlm.nih.gov/pubmed/36945491
http://dx.doi.org/10.1101/2023.03.07.530940

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