RPL26/uL24 UFMylation is essential for ribosome-associated quality control at the endoplasmic reticulum

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Ribosomes that stall while translating cytosolic proteins are incapacitated by incomplete nascent chains, termed “arrest peptides” (APs) that are destroyed by the ubiquitin proteasome system (UPS) via a process known as the ribosome-associated quality control (RQC) pathway. By contrast, APs on ribos...

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Detalles Bibliográficos
Autores principales: Scavone, Francesco, Gumbin, Samantha C., DaRosa, Paul A., Kopito, Ron R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028864/
https://www.ncbi.nlm.nih.gov/pubmed/36945571
http://dx.doi.org/10.1101/2023.03.08.531792

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