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Mapping the Complex Genetic Landscape of Human Neurons

When somatic cells acquire complex karyotypes, they are removed by the immune system. Mutant somatic cells that evade immune surveillance can lead to cancer. Neurons with complex karyotypes arise during neurotypical brain development, but neurons are almost never the origin of brain cancers. Instead...

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Detalles Bibliográficos
Autores principales: Sun, Chen, Kathuria, Kunal, Emery, Sarah B, Kim, ByungJun, Burbulis, Ian E., Shin, Joo Heon, Weinberger, Daniel R., Moran, John V., Kidd, Jeffrey M., Mills, Ryan E., McConnell, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028870/
https://www.ncbi.nlm.nih.gov/pubmed/36945473
http://dx.doi.org/10.1101/2023.03.07.531594