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RNA Sensing and Innate Immunity Constitutes a Barrier for Interspecies Chimerism

Interspecies chimera formation with human pluripotent stem cells (PSCs) holds great promise to generate humanized animal models and provide donor organs for transplant. However, the approach is currently limited by low levels of human cells ultimately represented in chimeric embryos. Different strat...

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Detalles Bibliográficos
Autores principales:	Hu, Yingying, Sun, Hai-Xi, Sakurai, Masahiro, Jones, Amanda E., Liu, Lizhong, Cheng, Tianlei, Zheng, Canbin, Li, Jie, Ravaux, Benjamin, Luo, Zhou, Ding, Yi, Liu, Tianbin, Wu, Yan, Chen, Elizabeth H., Chen, Zhijian J., Abrams, John M., Gu, Ying, Wu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028900/ https://www.ncbi.nlm.nih.gov/pubmed/36945615 http://dx.doi.org/10.1101/2023.03.07.531624

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