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Vaccination with mycobacterial lipid loaded nanoparticle leads to lipid antigen persistence and memory differentiation of antigen-specific T cells
Mycobacterium tuberculosis (Mtb) infection elicits both protein and lipid antigen-specific T cell responses. However, the incorporation of lipid antigens into subunit vaccine strategies and formulations has been underexplored, and the characteristics of vaccine-induced Mtb lipid-specific memory T ce...
Autores principales: | Morgun, Eva, Zhu, Jennifer, Almunif, Sultan, Bobbala, Sharan, Aguilar, Melissa S., Wang, Junzhong, Conner, Kathleen, Cui, Yongyong, Cao, Liang, Seshadri, Chetan, Scott, Evan A., Wang, Chyung-Ru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028924/ https://www.ncbi.nlm.nih.gov/pubmed/36945395 http://dx.doi.org/10.1101/2023.03.07.531489 |
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