Vaccination with mycobacterial lipid loaded nanoparticle leads to lipid antigen persistence and memory differentiation of antigen-specific T cells

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Mycobacterium tuberculosis (Mtb) infection elicits both protein and lipid antigen-specific T cell responses. However, the incorporation of lipid antigens into subunit vaccine strategies and formulations has been underexplored, and the characteristics of vaccine-induced Mtb lipid-specific memory T ce...

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Detalles Bibliográficos
Autores principales: Morgun, Eva, Zhu, Jennifer, Almunif, Sultan, Bobbala, Sharan, Aguilar, Melissa S., Wang, Junzhong, Conner, Kathleen, Cui, Yongyong, Cao, Liang, Seshadri, Chetan, Scott, Evan A., Wang, Chyung-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028924/
https://www.ncbi.nlm.nih.gov/pubmed/36945395
http://dx.doi.org/10.1101/2023.03.07.531489
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