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Endothelial Histone Deacetylase 1 Activity Impairs Kidney Microvascular NO Signaling in Rats fed a High Salt Diet

AIM: We aimed to identify new mechanisms by which a high salt diet (HS) decreases NO production in kidney microvascular endothelial cells. Specifically, we hypothesized HS impairs NO signaling through a histone deacetylase 1 (HDAC1)-dependent mechanism. METHODS: Male Sprague Dawley rats were fed nor...

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Detalles Bibliográficos
Autores principales:	Dunaway, Luke S., Cook, Anthony K., Botta, Davide, Molina, Patrick A., d’Uscio, Livius V., Katusic, Zvonimir S., Pollock, David M., Inscho, Edward W., Pollock, Jennifer S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028933/ https://www.ncbi.nlm.nih.gov/pubmed/36945391 http://dx.doi.org/10.1101/2023.03.08.531731

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