Mitochondrial electron transport chain, ceramide and Coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle

Insulin resistance (IR) is a complex metabolic disorder that underlies several human diseases, including type 2 diabetes and cardiovascular disease. Despite extensive research, the precise mechanisms underlying IR development remain poorly understood. Here, we provide new insights into the mechanist...

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Detalles Bibliográficos
Autores principales: Diaz-Vegas, Alexis, Madsen, Soren, Cooke, Kristen C., Carroll, Luke, Khor, Jasmine X. Y., Turner, Nigel, Lim, Xin Ying, Astore, Miro A., Morris, Jonathan, Don, Anthony, Garfield, Amanda, Zarini, Simona, Zemski Berry, Karin A., Ryan, Andrew, Bergman, Bryan C., Brozinick, Joseph T., James, David E., Burchfield, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028964/
https://www.ncbi.nlm.nih.gov/pubmed/36945619
http://dx.doi.org/10.1101/2023.03.10.532020

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