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Enzymatic Hydroxylation of Aliphatic C-H Bonds by a Mn/Fe Cofactor
Manganese cofactors activate strong chemical bonds in many essential enzymes. Yet very few manganese-dependent enzymes are known to functionalize ubiquitous carbon-hydrogen (C-H) bonds, and those that catalyze this important reaction display limited intrinsic reactivity. Herein, we report that the 2...
Autores principales: | Powell, Magan M., Rao, Guodong, Britt, R. David, Rittle, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029006/ https://www.ncbi.nlm.nih.gov/pubmed/36945426 http://dx.doi.org/10.1101/2023.03.10.532131 |
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