Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain

Genomic regulatory elements active in the developing human brain are notably enriched in genetic risk for neuropsychiatric disorders, including autism spectrum disorder (ASD), schizophrenia, and bipolar disorder. However, prioritizing the specific risk genes and candidate molecular mechanisms underl...

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Detalles Bibliográficos
Autores principales: Wen, Cindy, Margolis, Michael, Dai, Rujia, Zhang, Pan, Przytycki, Pawel F., Vo, Daniel D., Bhattacharya, Arjun, Matoba, Nana, Jiao, Chuan, Kim, Minsoo, Tsai, Ellen, Hoh, Celine, Aygün, Nil, Walker, Rebecca L., Chatzinakos, Christos, Clarke, Declan, Pratt, Henry, Consortium, PsychENCODE, Peters, Mette A., Gerstein, Mark, Daskalakis, Nikolaos P., Weng, Zhiping, Jaffe, Andrew E., Kleinman, Joel E., Hyde, Thomas M., Weinberger, Daniel R., Bray, Nicholas J., Sestan, Nenad, Geschwind, Daniel H., Roeder, Kathryn, Gusev, Alexander, Pasaniuc, Bogdan, Stein, Jason L., Love, Michael I., Pollard, Katherine S., Liu, Chunyu, Gandal, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029021/
https://www.ncbi.nlm.nih.gov/pubmed/36945630
http://dx.doi.org/10.1101/2023.03.03.23286706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029021/
https://www.ncbi.nlm.nih.gov/pubmed/36945630
http://dx.doi.org/10.1101/2023.03.03.23286706

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