T-cell activation, senescence, and exhaustion in asymptomatic HIV/Leishmania infantum co-infection

BACKGROUND: Leishmania infantum is an opportunistic parasitic infection. An immunocompromised state increases the risk of converting asymptomatic infection to symptomatic visceral leishmaniasis (VL), which has a ~5% fatality rate even with treatment. HIV coinfection increases the risk of death from...

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Detalles Bibliográficos
Autores principales: de Oliveira Mendes-Aguiar, Carolina, do Monte Alves, Manoella, de Albuquerque Lopes Machado, Amanda, de Góis Monteiro, Glória Regina, Medeiros, Iara Marques, Queiroz, Jose Wilton, Lima, Iraci Duarte, Pearson, Richard D., Wilson, Mary E., Glesby, Marshall J., do Nascimento, Eliana Lúcia Tomaz, Jerônimo, Selma Maria Bezerra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029033/
https://www.ncbi.nlm.nih.gov/pubmed/36945413
http://dx.doi.org/10.1101/2023.03.06.23286828

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