Spatial immunosampling of MRI-defined glioblastoma regions reveals immunologic fingerprint of non-contrast enhancing, infiltrative tumor margins

Glioblastoma (GBM) treatment includes maximal safe resection of the core and MRI contrast-enhancing (CE) tumor. Complete resection of the infiltrative non-contrast-enhancing (NCE) tumor rim is rarely achieved. We established a safe, semi-automated workflow for spatially-registered sampling of MRI-de...

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Detalles Bibliográficos
Autores principales: Grabowski, Matthew M., Watson, Dionysios C., Chung, Kunho, Lee, Juyeun, Bayik, Defne, Lauko, Adam, Alban, Tyler, Melenhorst, Jan Joseph, Chan, Timothy, Lathia, Justin D., Ahluwalia, Manmeet S., Mohammadi, Alireza M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029063/
https://www.ncbi.nlm.nih.gov/pubmed/36945620
http://dx.doi.org/10.1101/2023.03.09.23285970

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