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La-related protein 4 is enriched in vaccinia virus factories and is required for efficient viral replication in primary human fibroblasts
In addition to the 3'-poly(A) tail, vaccinia virus mRNAs synthesized after viral DNA replication (post-replicative mRNAs) possess a 5’-poly(A) leader that confers a translational advantage in virally infected cells. These mRNAs are synthesized in viral factories, the cytoplasmic compartment whe...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029068/ https://www.ncbi.nlm.nih.gov/pubmed/36945573 http://dx.doi.org/10.1101/2023.03.10.532125 |