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Transcriptomes of the tumor-adjacent normal tissues are more informative than tumors in predicting recurrence in colorectal cancer patients

BACKGROUND: Previous investigations of transcriptomic signatures of cancer patient survival and post-therapy relapse have focused on tumor tissue. In contrast, here we show that in colorectal cancer (CRC) transcriptomes derived from normal tissues adjacent to tumors (NATs) are better predictors of r...

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Detalles Bibliográficos
Autores principales: Kim, Jinho, Kim, Hyunjung, Lee, Min-Seok, Lee, Heetak, Kim, Yeon Jeong, Lee, Woo Yong, Yun, Seong Hyeon, Kim, Hee Cheol, Hong, Hye Kyung, Hannenhalli, Sridhar, Cho, Yong Beom, Park, Donghyun, Choi, Sun Shim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029176/
https://www.ncbi.nlm.nih.gov/pubmed/36941605
http://dx.doi.org/10.1186/s12967-023-04053-2

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