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Associations of genome-wide and regional autozygosity with 96 complex traits in old order Amish

Background: Autozygosity, the proportion of the genome that is homozygous by descent, has been associated with variation in multiple health-related traits impacting evolutionary fitness. Autozygosity (FROH) is typically measured from runs of homozygosity (ROHs) that arise when identical-by-descent (...

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Detalles Bibliográficos
Autores principales:	Lynch, Megan T., Maloney, Kristin A., Xu, Huichun, Perry, James A., Center, Regeneron Genetics, Shuldiner, Alan R., Mitchell, Braxton D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029202/ https://www.ncbi.nlm.nih.gov/pubmed/36941539 http://dx.doi.org/10.1186/s12864-023-09208-5

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