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Evaluation of the mTORC activity in the presence of Toxoplasma gondii and azathioprine in human monocyte cell line

BACKGROUND: Autophagy is an important part of pathogenesis of IBD. Thiopurines such as azathioprine (AZA) are approved drugs for clinical practices in IBD patients. Besides, as an escape strategy, Toxoplasma gondii can use the mTORC1 complex to inactivate autophagy. METHODS: In this study, we invest...

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Detalles Bibliográficos
Autores principales:	Nemati, Sara, Mohammad Rahimi, Hanieh, Meyfour, Anna, Pazoki, Hossein, Asadzadeh Aghdaei, Hamid, Shahrokh, Shabnam, Mirjalali, Hamed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029279/ https://www.ncbi.nlm.nih.gov/pubmed/36941573 http://dx.doi.org/10.1186/s12866-023-02819-8

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