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Placental mesenchymal stem cells ameliorate NLRP3 inflammasome-induced ovarian insufficiency by modulating macrophage M2 polarization

BACKGROUND: Premature ovarian insufficiency (POI) is a common clinical problem, however, there are currently no effective therapies. Pyroptosis induced by the NLRP3 inflammasome is considered a possible mechanism of POI. Placental mesenchymal stem cells (PMSCs) have excellent immunomodulatory potent...

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Detalles Bibliográficos
Autores principales: Chen, Dongmei, Hu, Na, Xing, Shasha, Yang, Li, Zhang, Feiyan, Guo, Songlin, Liu, Shudan, Ma, Xiaona, Liang, Xueyun, Ma, Huiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029285/
https://www.ncbi.nlm.nih.gov/pubmed/36945010
http://dx.doi.org/10.1186/s13048-023-01136-y

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