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Are threat perceptions associated with patient adherence to antibiotics? Insights from a survey regarding antibiotics and antimicrobial resistance among the Singapore public

BACKGROUND: Public health strategies to improve patient adherence to antibiotics rely mostly on raising awareness of the threat of antimicrobial resistance (AMR) and improving knowledge about antibiotics. We aimed to evaluate how adherence to antibiotics relates to knowledge and the threat perceptio...

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Autores principales: Lee, Si Yu, Shanshan, Yang, Lwin, May O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029286/
https://www.ncbi.nlm.nih.gov/pubmed/36941561
http://dx.doi.org/10.1186/s12889-023-15184-y
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author Lee, Si Yu
Shanshan, Yang
Lwin, May O.
author_facet Lee, Si Yu
Shanshan, Yang
Lwin, May O.
author_sort Lee, Si Yu
collection PubMed
description BACKGROUND: Public health strategies to improve patient adherence to antibiotics rely mostly on raising awareness of the threat of antimicrobial resistance (AMR) and improving knowledge about antibiotics. We aimed to evaluate how adherence to antibiotics relates to knowledge and the threat perceptions proposed by the Protection Motivation Theory (PMT). METHOD: A cross-sectional online survey was conducted in September-December 2020 with 1002 participants aged 21-70 years in Singapore. Two items, which were reverse coded, evaluated adherence to antibiotics: ‘how often do you obtain antibiotics that were left over from the previous prescription’ and ‘how often did you treat yourself with antibiotics in the past year’. Questions about the PMT-related constructs, and knowledge regarding antibiotics and AMR knowledge were also included. Hierarchical regression models were performed at a 5% significance level. RESULTS: Adherence to antibiotics was associated with knowledge level (β = 0.073, p < 0.05), education level (β = − 0.076, p < 0.01), and four of the five PMT constructs: “perceived response cost” (β = 0.61, p < 0.01), “perceived response efficacy of adherence to antibiotic” (β = 0.096, p < 0.01), “perceived susceptibility to AMR” (β = 0.097, p < 0.01), and “perceived severity of AMR” (β = − 0.069, p < 0.01). Knowledge about AMR, perceived self-efficacy in adhering to antibiotics, age, and sex were not associated with adherence. CONCLUSIONS: In Singapore, patient adherence to antibiotics appear to be driven by the perceived costs of visiting a doctor to obtain antibiotics, followed by perceptions of AMR as a threat and to a lesser extent, knowledge about antibiotics. Public health strategies to mitigate antibiotic misuse should consider these patient barriers to medical care. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-023-15184-y.
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spelling pubmed-100292862023-03-22 Are threat perceptions associated with patient adherence to antibiotics? Insights from a survey regarding antibiotics and antimicrobial resistance among the Singapore public Lee, Si Yu Shanshan, Yang Lwin, May O. BMC Public Health Research BACKGROUND: Public health strategies to improve patient adherence to antibiotics rely mostly on raising awareness of the threat of antimicrobial resistance (AMR) and improving knowledge about antibiotics. We aimed to evaluate how adherence to antibiotics relates to knowledge and the threat perceptions proposed by the Protection Motivation Theory (PMT). METHOD: A cross-sectional online survey was conducted in September-December 2020 with 1002 participants aged 21-70 years in Singapore. Two items, which were reverse coded, evaluated adherence to antibiotics: ‘how often do you obtain antibiotics that were left over from the previous prescription’ and ‘how often did you treat yourself with antibiotics in the past year’. Questions about the PMT-related constructs, and knowledge regarding antibiotics and AMR knowledge were also included. Hierarchical regression models were performed at a 5% significance level. RESULTS: Adherence to antibiotics was associated with knowledge level (β = 0.073, p < 0.05), education level (β = − 0.076, p < 0.01), and four of the five PMT constructs: “perceived response cost” (β = 0.61, p < 0.01), “perceived response efficacy of adherence to antibiotic” (β = 0.096, p < 0.01), “perceived susceptibility to AMR” (β = 0.097, p < 0.01), and “perceived severity of AMR” (β = − 0.069, p < 0.01). Knowledge about AMR, perceived self-efficacy in adhering to antibiotics, age, and sex were not associated with adherence. CONCLUSIONS: In Singapore, patient adherence to antibiotics appear to be driven by the perceived costs of visiting a doctor to obtain antibiotics, followed by perceptions of AMR as a threat and to a lesser extent, knowledge about antibiotics. Public health strategies to mitigate antibiotic misuse should consider these patient barriers to medical care. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-023-15184-y. BioMed Central 2023-03-20 /pmc/articles/PMC10029286/ /pubmed/36941561 http://dx.doi.org/10.1186/s12889-023-15184-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Lee, Si Yu
Shanshan, Yang
Lwin, May O.
Are threat perceptions associated with patient adherence to antibiotics? Insights from a survey regarding antibiotics and antimicrobial resistance among the Singapore public
title Are threat perceptions associated with patient adherence to antibiotics? Insights from a survey regarding antibiotics and antimicrobial resistance among the Singapore public
title_full Are threat perceptions associated with patient adherence to antibiotics? Insights from a survey regarding antibiotics and antimicrobial resistance among the Singapore public
title_fullStr Are threat perceptions associated with patient adherence to antibiotics? Insights from a survey regarding antibiotics and antimicrobial resistance among the Singapore public
title_full_unstemmed Are threat perceptions associated with patient adherence to antibiotics? Insights from a survey regarding antibiotics and antimicrobial resistance among the Singapore public
title_short Are threat perceptions associated with patient adherence to antibiotics? Insights from a survey regarding antibiotics and antimicrobial resistance among the Singapore public
title_sort are threat perceptions associated with patient adherence to antibiotics? insights from a survey regarding antibiotics and antimicrobial resistance among the singapore public
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029286/
https://www.ncbi.nlm.nih.gov/pubmed/36941561
http://dx.doi.org/10.1186/s12889-023-15184-y
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