Isoginkgetin-loaded reactive oxygen species scavenging nanoparticles ameliorate intervertebral disc degeneration via enhancing autophagy in nucleus pulposus cells

Excessive reactive oxygen species (ROS) in nucleus pulposus cells (NPCs) promote extracellular matrix (ECM) degradation and cellular inflammatory responses by activating a variety of cellular pathways, ultimately inducing cell apoptosis and leading to the development of low back pain. Here, we desig...

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Detalles Bibliográficos
Autores principales: Yu, Hao, Teng, Yun, Ge, Jun, Yang, Ming, Xie, Haifeng, Wu, Tianyi, Yan, Qi, Jia, Mengting, Zhu, Qing, Shen, Yanping, Zhang, Lianxue, Zou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029295/
https://www.ncbi.nlm.nih.gov/pubmed/36941611
http://dx.doi.org/10.1186/s12951-023-01856-9

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