Clinically oriented prediction of patient response to targeted and immunotherapies from the tumor transcriptome

BACKGROUND: Precision oncology is gradually advancing into mainstream clinical practice, demonstrating significant survival benefits. However, eligibility and response rates remain limited in many cases, calling for better predictive biomarkers. METHODS: We present ENLIGHT, a transcriptomics-based c...

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Detalles Bibliográficos
Autores principales: Dinstag, Gal, Shulman, Eldad D., Elis, Efrat, Ben-Zvi, Doreen S., Tirosh, Omer, Maimon, Eden, Meilijson, Isaac, Elalouf, Emmanuel, Temkin, Boris, Vitkovsky, Philipp, Schiff, Eyal, Hoang, Danh-Tai, Sinha, Sanju, Nair, Nishanth Ulhas, Lee, Joo Sang, Schäffer, Alejandro A., Ronai, Ze’ev, Juric, Dejan, Apolo, Andrea B., Dahut, William L., Lipkowitz, Stanley, Berger, Raanan, Kurzrock, Razelle, Papanicolau-Sengos, Antonios, Karzai, Fatima, Gilbert, Mark R., Aldape, Kenneth, Rajagopal, Padma S., Beker, Tuvik, Ruppin, Eytan, Aharonov, Ranit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029756/
https://www.ncbi.nlm.nih.gov/pubmed/36513065
http://dx.doi.org/10.1016/j.medj.2022.11.001

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