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Incidence of human papillomavirus–related cancers among males and females aged 15-34 years in the United States

Postmarket surveillance of the incidence of human papillomavirus (HPV)–related cancers is essential to monitor the effectiveness of HPV vaccines. We directly compared HPV-related cancer incidences during the pre- and postvaccine era to assess the effects of HPV vaccination among vaccine-eligible age...

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Detalles Bibliográficos
Autores principales: Guo, Fangjian, Adekanmbi, Victor, Hsu, Christine D, Berenson, Abbey B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029840/
https://www.ncbi.nlm.nih.gov/pubmed/36821427
http://dx.doi.org/10.1093/jncics/pkad016
Descripción
Sumario:Postmarket surveillance of the incidence of human papillomavirus (HPV)–related cancers is essential to monitor the effectiveness of HPV vaccines. We directly compared HPV-related cancer incidences during the pre- and postvaccine era to assess the effects of HPV vaccination among vaccine-eligible age groups in the United States using data from the US Cancer Statistics database. The 5-year average annual incidence rates for HPV-related cancers decreased in 2015-2019 compared with 2002-2006 among females aged 15-24 years and 25-34 years. Overall, a decrease in young males was not observed, whereas males aged 25-34 years experienced a slight decline in oropharyngeal squamous cell carcinoma between 2005-2009 and 2015-2019. Incidence rates for HPV-related cancers statistically significantly decreased in the vaccine era compared with the prevaccine era among females aged 15-34 years, suggesting the potential early effects of the introduction of HPV vaccination in the United States.