Cargando…

Real-Time Whole Genome Sequencing to Guide Patient-Tailored Therapy of Severe Acute Respiratory Syndrome Coronavirus 2 Infection

The management of coronavirus disease 2019 has become more complex due to the expansion of available therapies. The presence of severe acute respiratory syndrome coronavirus 2 variants and mutations further complicates treatment due to their differing susceptibilities to therapies. Here we outline t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Snell, Luke B, Alcolea-Medina, Adela, Charalampous, Themoula, Alder, Christopher, Williams, Tom G S, Flaviani, Flavia, Batra, Rahul, Bakrania, Prijay, Thangarajah, Rajeni, Neil, Stuart J D, van Nispen tot Pannerden, Claire, Botgros, Alina, Aarons, Emma, Douthwaite, Samuel T, Edgeworth, Jonathan D, Nebbia, Gaia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029986/ https://www.ncbi.nlm.nih.gov/pubmed/36327795 http://dx.doi.org/10.1093/cid/ciac864

Ejemplares similares

SARS-CoV-2 variants with shortened incubation periods necessitate new definitions for nosocomial acquisition
por: Snell, Luke B, et al.
Publicado: (2022)

Rapid genome sequencing in hospitals to identify potential vaccine-escape SARS-CoV-2 variants
por: Snell, Luke B, et al.
Publicado: (2021)

Feasibility and clinical utility of local rapid Nanopore influenza A virus whole genome sequencing for integrated outbreak management, genotypic resistance detection and timely surveillance
por: Williams, Tom G. S., et al.
Publicado: (2023)

Descriptive comparison of admission characteristics between pandemic waves and multivariable analysis of the association of the Alpha variant (B.1.1.7 lineage) of SARS-CoV-2 with disease severity in inner London
por: Snell, Luke B, et al.
Publicado: (2022)

Broad Neutralization of SARS-CoV-2 Variants, Including Omicron, following Breakthrough Infection with Delta in COVID-19-Vaccinated Individuals
por: Lechmere, Thomas, et al.
Publicado: (2022)

Endogenous antibody responses in REGN-COV2-treated SARS-CoV-2-infected individuals
por: Kurshan, Ashwini, et al.
Publicado: (2023)

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series
por: Patel, Aatish, et al.
Publicado: (2022)

Comparative performance of SARS-CoV-2 lateral flow antigen tests and association with detection of infectious virus in clinical specimens: a single-centre laboratory evaluation study
por: Pickering, Suzanne, et al.
Publicado: (2021)

Combined epidemiological and genomic analysis of nosocomial SARS-CoV-2 infection early in the pandemic and the role of unidentified cases in transmission
por: Snell, Luke B., et al.
Publicado: (2022)

Evaluating the potential for respiratory metagenomics to improve treatment of secondary infection and detection of nosocomial transmission on expanded COVID-19 intensive care units
por: Charalampous, Themoula, et al.
Publicado: (2021)

P25 Ceftazidime/avibactam and cefiderocol use in adults in a South London Trust
por: Kmentt, Laura, et al.
Publicado: (2023)

P37 Variable adherence to and effectiveness of a vancomycin continuous infusion protocol within ICUs at a London tertiary-care hospital: a single-centre retrospective service evaluation
por: Oakley, Robert, et al.
Publicado: (2022)

Clinical utility of targeted SARS-CoV-2 serology testing to aid the diagnosis and management of suspected missed, late or post-COVID-19 infection syndromes: Results from a pilot service implemented during the first pandemic wave
por: Sweeney, Nicola, et al.
Publicado: (2021)

Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern
por: Dupont, Liane, et al.
Publicado: (2021)

Antibody longevity and cross-neutralizing activity following SARS-CoV-2 wave 1 and B.1.1.7 infections
por: Dupont, Liane, et al.
Publicado: (2021)

Real-world deployment of lateral flow SARS-CoV-2 antigen detection in the emergency department to provide rapid, accurate and safe diagnosis of COVID-19
por: Merrick, B., et al.
Publicado: (2021)

A comparative evaluation between the Abbott Panbio™ COVID-19 IgG/IgM rapid test device and Abbott Architect™ SARS CoV-2 IgG assay
por: Batra, Rahul, et al.
Publicado: (2020)

Nosocomial acquisition of influenza is associated with significant morbidity and mortality: Results of a prospective observational study
por: Snell, L.B., et al.
Publicado: (2022)

Translational Research in the Time of COVID-19—Dissolving Boundaries
por: Edgeworth, Jonathan D., et al.
Publicado: (2020)

VirA+EmiC project: Evaluating real‐world effectiveness and sustainability of integrated routine opportunistic hepatitis B and C testing in a large urban emergency department
por: Nebbia, Gaia, et al.
Publicado: (2022)

An innovative approach to increase viral hepatitis diagnoses and linkage to care using opt-out testing and an integrated care pathway in a London Emergency Department
por: Evans, Hannah, et al.
Publicado: (2018)

A framework for real-time monitoring, analysis and adaptive sampling of viral amplicon nanopore sequencing
por: Munro, Rory, et al.
Publicado: (2023)

SARS-CoV-2 lineage B.1.1.7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study
por: Stirrup, Oliver, et al.
Publicado: (2021)

Real-world evaluation of a novel technology for quantitative simultaneous antibody detection against multiple SARS-CoV-2 antigens in a cohort of patients presenting with COVID-19 syndrome
por: Shaw, Andrew M., et al.
Publicado: (2020)

Neurogenesis is disrupted in human hippocampal progenitor cells upon exposure to serum samples from hospitalized COVID-19 patients with neurological symptoms
por: Borsini, Alessandra, et al.
Publicado: (2022)

Reductions in Methicillin-resistant Staphylococcus aureus, Clostridium difficile Infection and Intensive Care Unit–Acquired Bloodstream Infection Across the United Kingdom Following Implementation of a National Infection Control Campaign
por: Edgeworth, Jonathan D, et al.
Publicado: (2020)

Universal testing for hepatitis B and hepatitis C in the emergency department: a cost-effectiveness and budget impact analysis of two urban hospitals in the United Kingdom
por: Williams, Jack, et al.
Publicado: (2022)

Antimicrobial multidrug resistance in the era of COVID-19: a forgotten plight?
por: Pelfrene, Eric, et al.
Publicado: (2021)

COVID-19: stewardship of diagnostic tests for bacterial co-infection
por: Williams, Tom G S, et al.
Publicado: (2021)

Prevalence of Gram-negative bacilli resistance in adult critically ill patients at admission screening
por: Kotwinski, D, et al.
Publicado: (2011)

Urinary antigen testing for respiratory infection during COVID-19: The microbiologist as a diagnostic steward
por: Williams, Tom, et al.
Publicado: (2022)

Reductions in MRSA, Clostridium difficile and Intensive Care Unit (ICU) Acquired Bloodstream Infections and over 9 years from 276 United Kingdom ICUs
por: Batra, Rahul, et al.
Publicado: (2017)

2164. A Feasibility Study to Investigate the Spread of Antimicrobial Resistance in the Community Suggests Ongoing Dissemination Within Households
por: Batra, Rahul, et al.
Publicado: (2018)

2471. Review of Methicillin-Resistant Staphylococcus aureus, Clostridium difficile and Acquired Bloodstream Infections Across all United Kingdom Intensive Care Units following Implementation of a Statutory National Infection Control Campaign.
por: Batra, Rahul, et al.
Publicado: (2019)

Tailoring dissemination strategies to increase evidence-informed policymaking for opioid use disorder treatment: study protocol
por: Crable, Erika L., et al.
Publicado: (2023)

Biosecurity and Hygiene Procedures in Pig Farms: Effects of a Tailor-Made Approach as Monitored by Environmental Samples
por: Scollo, Annalisa, et al.
Publicado: (2023)

The Effects of Two Thick Film Deposition Methods on Tin Dioxide Gas Sensor Performance
por: Bakrania, Smitesh D., et al.
Publicado: (2009)

The Effects of the Location of Au Additives on Combustion-generated SnO(2) Nanopowders for CO Gas Sensing
por: Bakrania, Smitesh D., et al.
Publicado: (2010)

Correction: Tailoring dissemination strategies to increase evidence-informed policymaking for opioid use disorder treatment: study protocol
por: Crable, Erika L., et al.
Publicado: (2023)

Quantifying Type-Specific Reproduction Numbers for Nosocomial Pathogens: Evidence for Heightened Transmission of an Asian Sequence Type 239 MRSA Clone
por: Cooper, Ben S., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_r8ldtbln8b1qppsgen3g1cpghe