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Iron status influences mitochondrial disease progression in Complex I-deficient mice

Mitochondrial dysfunction caused by aberrant Complex I assembly and reduced activity of the electron transport chain is pathogenic in many genetic and age-related diseases. Mice missing the Complex I subunit NADH dehydrogenase [ubiquinone] iron-sulfur protein 4 (NDUFS4) are a leading mammalian model...

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Detalles Bibliográficos
Autores principales:	Kelly, CJ, Couch, Reid K, Ha, Vivian T, Bodart, Camille M, Wu, Judy, Huff, Sydney, Herrel, Nicole T, Kim, Hyunsung D, Zimmermann, Azaad O, Shattuck, Jessica, Pan, Yu-Chen, Kaeberlein, Matt, Grillo, Anthony S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2023
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030112/ https://www.ncbi.nlm.nih.gov/pubmed/36799301 http://dx.doi.org/10.7554/eLife.75825

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