Hepatic lipid overload triggers biliary epithelial cell activation via E2Fs

During severe or chronic hepatic injury, biliary epithelial cells (BECs) undergo rapid activation into proliferating progenitors, a crucial step required to establish a regenerative process known as ductular reaction (DR). While DR is a hallmark of chronic liver diseases, including advanced stages o...

Descripción completa

Detalles Bibliográficos
Autores principales: Yildiz, Ece, El Alam, Gaby, Perino, Alessia, Jalil, Antoine, Denechaud, Pierre-Damien, Huber, Katharina, Fajas, Lluis, Auwerx, Johan, Sorrentino, Giovanni, Schoonjans, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030116/
https://www.ncbi.nlm.nih.gov/pubmed/36876915
http://dx.doi.org/10.7554/eLife.81926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030116/
https://www.ncbi.nlm.nih.gov/pubmed/36876915
http://dx.doi.org/10.7554/eLife.81926

Ejemplares similares