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Hepatic lipid overload triggers biliary epithelial cell activation via E2Fs
During severe or chronic hepatic injury, biliary epithelial cells (BECs) undergo rapid activation into proliferating progenitors, a crucial step required to establish a regenerative process known as ductular reaction (DR). While DR is a hallmark of chronic liver diseases, including advanced stages o...
Autores principales: | Yildiz, Ece, El Alam, Gaby, Perino, Alessia, Jalil, Antoine, Denechaud, Pierre-Damien, Huber, Katharina, Fajas, Lluis, Auwerx, Johan, Sorrentino, Giovanni, Schoonjans, Kristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030116/ https://www.ncbi.nlm.nih.gov/pubmed/36876915 http://dx.doi.org/10.7554/eLife.81926 |
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