Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses

To address the ongoing SARS-CoV-2 pandemic and prepare for future coronavirus outbreaks, understanding the protective potential of epitopes conserved across SARS-CoV-2 variants and coronavirus lineages is essential. We describe a highly conserved, conformational S2 domain epitope present only in the...

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Detalles Bibliográficos
Autores principales: Silva, Rui P, Huang, Yimin, Nguyen, Annalee W, Hsieh, Ching-Lin, Olaluwoye, Oladimeji S, Kaoud, Tamer S, Wilen, Rebecca E, Qerqez, Ahlam N, Park, Jun-Gyu, Khalil, Ahmed M, Azouz, Laura R, Le, Kevin C, Bohanon, Amanda L, DiVenere, Andrea M, Liu, Yutong, Lee, Alison G, Amengor, Dzifa A, Shoemaker, Sophie R, Costello, Shawn M, Padlan, Eduardo A, Marqusee, Susan, Martinez-Sobrido, Luis, Dalby, Kevin N, D'Arcy, Sheena, McLellan, Jason S, Maynard, Jennifer A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030117/
https://www.ncbi.nlm.nih.gov/pubmed/36942851
http://dx.doi.org/10.7554/eLife.83710

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