Cargando…

Attenuation of cancer proliferation by suppression of glypican-1 and its pleiotropic effects in neoplastic behavior

Glypicans (GPC1-6) are associated with tumorigenic processes and their involvement in neoplastic behavior has been discussed in different cancer types. Here, a cancer-wide GPC expression study, using clinical cancer patient data in The Cancer Genome Atlas, reveals net upregulation of GPC1 and GPC2 i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Fang, Hansson, Victor Chérouvrier, Georgolopoulos, Grigorios, Mani, Katrin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030152/ https://www.ncbi.nlm.nih.gov/pubmed/36944188 http://dx.doi.org/10.18632/oncotarget.28388

Ejemplares similares

Pleiotropic Role of HSF1 in Neoplastic Transformation
por: Vydra, Natalia, et al.
Publicado: (2014)

Complex modulation of cytokine-induced α-synuclein aggregation by glypican-1-derived heparan sulfate in neural cells
por: Cheng, Fang, et al.
Publicado: (2021)

Interplay between APP and glypican-1 processing and α-synuclein aggregation in undifferentiated and differentiated human neural progenitor cells
por: Cheng, Fang, et al.
Publicado: (2023)

Glypicans
por: Filmus, Jorge, et al.
Publicado: (2008)

Proinflammatory cytokines induce accumulation of glypican-1-derived heparan sulfate and the C-terminal fragment of β-cleaved APP in autophagosomes of dividing neuronal cells
por: Cheng, Fang, et al.
Publicado: (2020)

Autophagy suppresses proliferation of HepG2 cells via inhibiting glypican-3/wnt/β-catenin signaling
por: Hu, Pei, et al.
Publicado: (2018)

Improvements in the order, isotropy and electron density of glypican-1 crystals by controlled dehydration
por: Awad, Wael, et al.
Publicado: (2013)

Glypican-5 stimulates rhabdomyosarcoma cell proliferation by activating Hedgehog signaling
por: Li, Fuchuan, et al.
Publicado: (2011)

Brief Report: A Differential Transcriptomic Profile of Ex Vivo Expanded Adult Human Hematopoietic Stem Cells Empowers Them for Engraftment Better than Their Surface Phenotype
por: Psatha, Nikoletta, et al.
Publicado: (2017)

Unbiased phenotypic identification of functionally distinct hematopoietic progenitors
por: Georgolopoulos, Grigorios, et al.
Publicado: (2019)

Glypican-1-targeted and gemcitabine-loaded liposomes enhance tumor-suppressing effect on pancreatic cancer
por: Mu, Yu, et al.
Publicado: (2020)

Primary cilia attenuate hedgehog signalling in neoplastic chondrocytes
por: Ho, L, et al.
Publicado: (2013)

Metformin Beyond Diabetes: Pleiotropic Benefits of Metformin in Attenuation of Atherosclerosis
por: Forouzandeh, Farshad, et al.
Publicado: (2014)

Glypican 1 promotes proliferation and migration in esophagogastric adenocarcinoma via activating AKT/GSK/β-catenin pathway
por: Pratap, Akshay, et al.
Publicado: (2022)

Cancer immunotherapy‐targeted glypican‐3 or neoantigens
por: Shimizu, Yasuhiro, et al.
Publicado: (2018)

Diagnostic Value of Glypican-3 for Hepatocellular Carcinomas
por: El-Saadany, Sherif, et al.
Publicado: (2018)

Glypican 3 as a Serum Marker for Hepatoblastoma
por: Zhou, Shengmei, et al.
Publicado: (2017)

Glypican 3-Targeted Therapy in Hepatocellular Carcinoma
por: Nishida, Takahiro, et al.
Publicado: (2019)

Glypicans and cytonemes unite to distribute Wnt ligands
por: Waghmare, Indrayani, et al.
Publicado: (2021)

Neuroendocrine Tumors Show Altered Expression of Chondroitin Sulfate, Glypican 1, Glypican 5, and Syndecan 2 Depending on Their Differentiation Grade
por: García-Suárez, Olivia, et al.
Publicado: (2014)

The Glypican-1/HGF/C-Met and Glypican-1/VEGF/VEGFR2 Ternary Complexes Regulate Hair Follicle Angiogenesis
por: Colin-Pierre, Charlie, et al.
Publicado: (2021)

Glypican-5 suppresses Epithelial-Mesenchymal Transition of the lung adenocarcinoma by competitively binding to Wnt3a
por: Wang, Siwei, et al.
Publicado: (2016)

Albendazole Exhibits Anti-Neoplastic Actions against Gastric Cancer Cells by Affecting STAT3 and STAT5 Activation by Pleiotropic Mechanism(s)
por: Yang, Min Hee, et al.
Publicado: (2021)

Pleiotropic Control by Testosterone of a Learned Vocal Behavior and Its Underlying Neuroplasticity123
por: Alward, Beau A., et al.
Publicado: (2016)

Normal and Neoplastic Growth Suppression by the Extended Myc Network
por: Prochownik, Edward V., et al.
Publicado: (2022)

Targeted glypican-3 gene transcription inhibited the proliferation of human hepatoma cells by specific short hairpin RNA
por: Yu, Dandan, et al.
Publicado: (2012)

Glypican and Biglycan in the Nuclei of Neurons and Glioma Cells: Presence of Functional Nuclear Localization Signals and Dynamic Changes in Glypican During the Cell Cycle
por: Liang, Yu, et al.
Publicado: (1997)

CD142 Identifies Neoplastic Desmoid Tumor Cells, Uncovering Interactions Between Neoplastic and Stromal Cells That Drive Proliferation
por: Al-Jazrawe, Mushriq, et al.
Publicado: (2023)

Differential expression of syndecans and glypicans in chronically inflamed synovium
por: Patterson, A M, et al.
Publicado: (2008)

Methylation analysis of the glypican 3 gene in embryonal tumours
por: Boily, G, et al.
Publicado: (2004)

Expression of glypican 3 in placental site trophoblastic tumor
por: Ou-Yang, Robin J, et al.
Publicado: (2010)

Drosophila glypicans regulate the germline stem cell niche
por: Hayashi, Yoshiki, et al.
Publicado: (2009)

Glypican Is a Modulator of Netrin-Mediated Axon Guidance
por: Blanchette, Cassandra R., et al.
Publicado: (2015)

Novel insights into Notum and glypicans regulation in colorectal cancer
por: De Robertis, Mariangela, et al.
Publicado: (2015)

Glypican-3 Targeting Immunotoxins for the Treatment of Liver Cancer
por: Fleming, Bryan D., et al.
Publicado: (2016)

The Expression, Regulation, and Biomarker Potential of Glypican-1 in Cancer
por: Wang, Sen, et al.
Publicado: (2019)

Can glypican-3 be a disease-specific biomarker?
por: Chen, Chaolei, et al.
Publicado: (2017)

Next-Generation Cancer Immunotherapy Targeting Glypican-3
por: Shimizu, Yasuhiro, et al.
Publicado: (2019)

Glypican-1 in human glioblastoma: implications in tumorigenesis and chemotherapy
por: Listik, Eduardo, et al.
Publicado: (2020)

Glypican-1 Overexpression in Different Types of Breast Cancers
por: Alshammari, Fatemah O F O, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qcka96n6mjll3bltn0tiq3aepu