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Identification of hypertrophy-modulating Cullin-RING ubiquitin ligases in primary cardiomyocytes

Cullin-RING ubiquitin ligases (CRL) regulate numerous biological processes in the heart and have been implicated in regulating cardiac hypertrophy. This study aimed to identify novel hypertrophy-modulating CRLs in cardiomyocytes (CM). A functional genomic approach using siRNA-mediated depletion and...

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Detalles Bibliográficos
Autores principales:	Fischer, Maximillian, Jakab, Moritz, Hirt, Marc N., Werner, Tessa R., Engelhardt, Stefan, Sarikas, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030680/ https://www.ncbi.nlm.nih.gov/pubmed/36969608 http://dx.doi.org/10.3389/fphys.2023.1134339

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