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Comparative in vitro treatment of mesenchymal stromal cells with GDF-5 and R57A induces chondrogenic differentiation while limiting chondrogenic hypertrophy

PURPOSE: Hypertrophic cartilage is an important characteristic of osteoarthritis and can often be found in patients suffering from osteoarthritis. Although the exact pathomechanism remains poorly understood, hypertrophic de-differentiation of chondrocytes also poses a major challenge in the cell-bas...

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Detalles Bibliográficos
Autores principales:	Weißenberger, Manuel, Wagenbrenner, Mike, Nickel, Joachim, Ahlbrecht, Rasmus, Blunk, Torsten, Steinert, Andre F., Gilbert, Fabian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030724/ https://www.ncbi.nlm.nih.gov/pubmed/36943593 http://dx.doi.org/10.1186/s40634-023-00594-z

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