Cargando…

CCN2/CTGF promotes liver fibrosis through crosstalk with the Slit2/Robo signaling

Liver fibrosis is the common outcome of many chronic liver diseases, resulting from altered cell-cell and cell-matrix interactions that promote hepatic stellate cell (HSC) activation and excessive matrix production. This study aimed to investigate functions of cellular communication network factor 2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pi, Liya, Sun, Chunbao, Jn-Simon, Natacha, Basha, Sreenivasulu, Thomas, Haven, Figueroa, Victoria, Zarrinpar, Ali, Cao, Qi, Petersen, Bryon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030765/ https://www.ncbi.nlm.nih.gov/pubmed/36469291 http://dx.doi.org/10.1007/s12079-022-00713-y

Ejemplares similares

The SLIT/ROBO Pathway in Liver Fibrosis and Cancer
por: Basha, Sreenivasulu, et al.
Publicado: (2023)

Crosstalk between the activated Slit2–Robo1 pathway and TGF‐β1 signalling promotes cardiac fibrosis
por: Liu, Yunqi, et al.
Publicado: (2020)

A potential role for CCN2/CTGF in aggressive colorectal cancer
por: Ubink, Inge, et al.
Publicado: (2016)

CCN2/CTGF promotor activity in the developing and adult mouse eye
por: Dillinger, Andrea E., et al.
Publicado: (2021)

CCN2/CTGF—A Modulator of the Optic Nerve Head Astrocyte
por: Dillinger, Andrea E., et al.
Publicado: (2022)

Slit–Robo signalling in heart development
por: Zhao, Juanjuan, et al.
Publicado: (2018)

The Role of the Slit/Robo Signaling Pathway
por: Tong, Mingfu, et al.
Publicado: (2019)

Role of Matricellular CCN Proteins in Skeletal Muscle: Focus on CCN2/CTGF and Its Regulation by Vasoactive Peptides
por: Rebolledo, Daniela L., et al.
Publicado: (2021)

New strategy to control cell migration and metastasis regulated by CCN2/CTGF
por: Aguiar, Diego Pinheiro, et al.
Publicado: (2014)

Potential Renoprotective Agents through Inhibiting CTGF/CCN2 in Diabetic Nephropathy
por: Wang, Songyan, et al.
Publicado: (2015)

Robo2 is required for Slit-mediated intraretinal axon guidance
por: Thompson, Hannah, et al.
Publicado: (2009)

Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons
por: Evans, Timothy A, et al.
Publicado: (2015)

Global expression profiling reveals regulation of CTGF/CCN2 during lactogenic differentiation
por: Wang, Weihan, et al.
Publicado: (2009)

Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animals
por: Brigstock, David R.
Publicado: (2009)

Driving fibrosis in neuromuscular diseases: Role and regulation of Connective tissue growth factor (CCN2/CTGF)
por: Rebolledo, Daniela L., et al.
Publicado: (2021)

Slit/Robo signaling regulates Leydig cell steroidogenesis
por: Martinot, Emmanuelle, et al.
Publicado: (2021)

Role of Slit/Robo Signaling pathway in Bone Metabolism
por: Jiang, Lingyu, et al.
Publicado: (2022)

Effect of Slit/Robo signaling on regeneration in lung emphysema
por: Park, Jin-Soo, et al.
Publicado: (2021)

CCN family member 2/connective tissue growth factor (CCN2/CTGF) is regulated by Wnt–β-catenin signaling in nucleus pulposus cells
por: Hiyama, Akihiko, et al.
Publicado: (2018)

The Notochord, Notochordal cell and CTGF/CCN-2: ongoing activity from development through maturation
por: Erwin, W. Mark
Publicado: (2008)

CTGF/CCN2 Postconditioning Increases Tolerance of Murine Hearts towards Ischemia-Reperfusion Injury
por: Kaasbøll, Ole Jørgen, et al.
Publicado: (2016)

Complement 3a Mediates CCN2/CTGF in Human Retinal Pigment Epithelial Cells
por: Xiao, Kang, et al.
Publicado: (2022)

Blocking CTGF/CCN2 reduces established skeletal muscle fibrosis in a rat model of overuse injury
por: Barbe, Mary F., et al.
Publicado: (2020)

Slit2 and Robo3 modulate the migration of GnRH-secreting neurons
por: Cariboni, Anna, et al.
Publicado: (2012)

Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signaling
por: Alpár, Alán, et al.
Publicado: (2014)

Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma
por: Marko, Tracy A., et al.
Publicado: (2016)

Matricellular proteins of the Cyr61/CTGF/NOV (CCN) family and the nervous system
por: Malik, Anna R., et al.
Publicado: (2015)

Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes
por: Wang, Xiaoyu, et al.
Publicado: (2010)

Coevolution of Axon Guidance Molecule Slit and Its Receptor Robo
por: Yu, Qi, et al.
Publicado: (2014)

Vascular control of the Drosophila haematopoietic microenvironment by Slit/Robo signalling
por: Morin-Poulard, Ismaël, et al.
Publicado: (2016)

Contralateral migration of oculomotor neurons is regulated by Slit/Robo signaling
por: Bjorke, Brielle, et al.
Publicado: (2016)

Slit-independent guidance of longitudinal axons by Drosophila Robo3
por: Carranza, Abigail, et al.
Publicado: (2023)

Connective Tissue Growth Factor (CTGF/CCN2) Is Negatively Regulated during Neuron-Glioblastoma Interaction
por: Romão, Luciana F., et al.
Publicado: (2013)

CCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stress
por: Hall-Glenn, Faith, et al.
Publicado: (2013)

Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex
por: Ercan, Ebru, et al.
Publicado: (2017)

Dynamic Malignant Wave of Ribosome-Insulted Gut Niche via the Wnt-CTGF/CCN2 Circuit
por: Kim, Ki Hyung, et al.
Publicado: (2020)

SLIT2/ROBO1-signaling inhibits macropinocytosis by opposing cortical cytoskeletal remodeling
por: Bhosle, Vikrant K., et al.
Publicado: (2020)

Liver regeneration and ethanol detoxification: A new link in YAP regulation of ALDH1A1 during alcohol‐related hepatocyte damage
por: Zhou, Junmei, et al.
Publicado: (2022)

Epigenetics and expression of key genes associated with cardiac fibrosis: NLRP3, MMP2, MMP9, CCN2/CTGF and AGT
por: Chandra, Sruti, et al.
Publicado: (2021)

A structural approach to the role of CCN (CYR61/CTGF/NOV) proteins in tumourigenesis
por: Planque, Nathalie, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_teiglb1digbp7r7qrs5o53h6k5